The Clinical Neuroscience
Unit is a neuroscience
laboratory at the
Neurological Clinic
of the University of Bonn.

It is headed by
Prof. Dr. Michael. T.



Deutsch (DE-CH-AT)English (United Kingdom)



Phone: 0228 287-13091




University Hospital Bonn
Clinic and Polyclinic
for Neurology
Clinical Neuroscience
Sigmund-Freud-Straße 25
53127 Bonn, Germany

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Welcome to the Heneka Lab!


Improved preventive, disease modifying, and acute therapy for patients suffering from neurodegenerative disease.


Clinical, translational and experimental studies to improve our understanding of patients needs, therapeutic interventions and disease pathogenesis.

Clinic and Research

Despite increasing research efforts our current therapeutic options for the treatment of all major neurodegenerative disorders are limited. Although, most of these diseases have been described a long time ago, no effective therapeutic interventions have been developed so far. Therefore, the major aim of our work is to improve the understanding of all factors that are involved in development of these diseases. The overarching goal is to translate new knowlegde into the clinic to prevent the  development of neurodegenerative diseases, to modify the disease course, and to provide effective therapeutics to patients who already suffer. Our scientific work focuses on the characterisation of innate immune mechanisms in Alzheimer`s disease, amyotrophic lateral sclerosis (ALS), Parkinson`s disease and others. We hope to identify biomarkers for early disease detection and to uncover disease mechanisms which offer targets for theurapeutic intervention.



Ear2 Deletion Causes Early Memory and Learning Deficits in APP/PS1 Mice.
Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT. 
J Neurosci. 2014 Jun 25;34(26):8845-54.


Innate immune activation in neurodegenerative disease.
Michael T. Heneka, Markus P. Kummer, Eicke Latz 
Nat Rev Immunol. 2014 Jun 25;14(7):463-77.



Long-term cerebral consequences of sepsis.
Catherine N. Widmann and Michael T. Heneka
Lancet Neurol. Jun 2014; 13(6):630-6.